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killing to send a message to gun rights activists, according to a Mother Jones report that investigated the claim. Marchetti et al. examined the costs of six different ADHD drug therapies: generic and branded (Ritalin) MPH immediate release (IR) therapies, two branded MPH extended release (ER) therapies (Concerta and Metadate CD), generic MPH IR/ER, and a combination therapy of amphetamine salts (Adderall). The annual expected cost of treatment with each drug therapy, including costs incurred with physician visits and lab exams, was highest for Adderall at $2,567 (2004 US $) and lowest for Metadate CD at $1,710. The cost for the other therapies ranged from $2,061 (Concerta) to $2,392 (Ritalin). Results from the initial binary logistic regression (additive model) are shown in Table 4 (goodness-of-fit tests for this model are shown in Table 5 ). Predictor values with P -values less than 0.1 were retained (ie, prescription/OTC pain-reliever use was omitted) in subsequent regressions. Backward stepwise binary logistic regression was conducted using the remaining significant predictor variables: no group affiliation, difficulty sleeping, and nicotine craving. Since bivariate correlations found a significant correlation of difficulty sleeping with nicotine craving, the interaction variable & x0201c;difficulty sleeping & x000d7; nicotine craving& x0201d; was also assessed. Two additional binary logistic regressions were performed by entering the main effects before interaction effects (ie, no group affiliation entered before difficulty sleeping & x000d7; nicotine craving, followed by nicotine craving [lowest P -value in the additive model] and either difficulty sleeping or no group affiliation). The Controlled Substances Act (CSA) regulates the manufacturing and possession of controlled substances. The CSA categorizes drugs, substances, and certain chemicals that are used to make drugs into five distinct classifications or schedules depending on a drug medical use and potential for abuse. 5 All Adderall products are listed as a Schedule II controlled substance under the CSA. 6. The slower breakdown and
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